Generic VIAGRA – Dosages, Warnings, Side Effects, Interactions, Prices

Basic Information about Viagra

Viagra (active ingredient sildenafil citrate) is the brand name medication used primarily for managing problems with erection. This condition may require treatment with drugs when a man is unable to have sexual intercourse in more than 50% of attempts. There may be different reasons for this condition resulting in the insufficient blow flow to the penis. Thanks to Viagra, certain muscles of the body relax, which allows the blood flow to reach the penis without obstacles. Viagra has been proven to be relatively safe and effective for nearly 60-80% of men.

Viagra Metabolization

The active ingredient is broken down in the liver using CYP2C9 hepatic isoenzymes and cytochrome p450 enzymes. As a result, different products of metabolization are produced, including N- Desmethyl sildenafil, which is a major metabolite of sildenafil. This metabolite is responsible for nearly 20% of the action of the ingredient. Sildenafil is excreted mainly in the feces (around 80% of the dosage administered orally) and in the urine (about 13% of the dosage administered orally). Absorption is reduced if the drug is taken along with a high-fat meal. It takes about one hour to reach the maximum concentration.

Dosages

The recommended dosage of Viagra is 50mg, but it may be prescribed in a dosage ranging from 25mg to 100mg based on the individual circumstance of a man. The drug is taken one hour before sexual intercourse. It will not work without sexual stimulation.

Viagra may be taken with/without food, but it is important to mind that some products consumed along with this drug may affect its effectiveness, including alcohol and products from grapefruit. This medication should be taken no more than one time per day.

Warnings

Some health conditions require caution when the medicine is prescribed, including those related to heart, kidney, vision, blood, or liver disorders. It is important to make sure that a man can use this drug safely, and that is why consulting with a healthcare provider is necessary. Tell your doctor about all health problems and symptoms that you may have, especially those experienced during sexual activity.

The medicine can be used only by men over eighteen years old.

Side Effects

Common side effects that may occur due to the drug:

  • Diarrhea;
  • Dizziness;
  • Headache;
  • Nosebleeds;
  • Sensitivity to light;
  • Heartburn;
  • Numbness/tingling in limbs;
  • Upset stomach;
  • Insomnia;
  • Runny/stuffy nose;
  • Muscle pain;
  • Flushing;
  • Vision color changes.

Serious side effects that may occur due to Viagra:

  • Severe vision problems;
  • Shortness of breath;
  • A long-lasting erection;
  • Heart attack symptoms;
  • Irregular heartbeat;
  • Swelling in certain part of the body;
  • Severe hearing problems;
  • Seizures;
  • Rash;
  • Burning/itching during urinating;
  • Allergic reaction.

Viagra Interactions

It is important to avoid drug interaction. Tell your health provider about all prescription, non-prescription, generic, brand, herbal, recreational, nutritional, or dietary medications that you use. The following drugs should never be combined with Viagra:

  • Alpha blockers, including alfuzosin, doxazosin, prazosin, and others;
  • Certain antifungals, including itraconazole, ketoconazole, and others;
  • Blood thinners, including warfarin and others;
  • Certain barbiturates, including butalbital, secobarbital, and others;
  • Beta-blockers, including atenolol, labetalol, metoprolol, nadolol, and others.
  • HIV protease inhibitors, including atazanavir, darunavir, fosamprenavir, and others;
  • Other ED drugs;
  • Drugs for high blood pressure;
  • Certain medicines for seizures, including carbamazepine, phenytoin, and others.